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Let’s talk estrogen

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If you’ve ever been on hormonal birth control or looked at what’s out there, you know there are a lot of options.
And chances are that you know these options are supposed to be different, but how are they different?

If you’ve ever been on hormonal birth control or looked at what’s out there, you know there are a lot of options. And chances are that you know these options are supposed to be different, but how are they different?

Let’s review the
2 key components
of
many hormonal
birth control options

There are many kinds of progestin, but you may be
surprised to learn how limited your choices have been
when it comes to estrogen, until now.

There are many kinds of progestin, but
you may be surprised to learn how limited your choices have been when it comes to estrogen, until now.

THE QUIZ

See how much you know about
estrogen in birth control pills.

the quiz 1 of 6

What is the main role of estrogen in birth control pills
(hint, look up—the answer is on this page)?

  • A Responsible for stopping
    ovulation
  • B Helps prevent unwanted
    changes in your
    menstrual
    cycle when avoiding
    pregnancy

the quiz 2 of 6

How many types of estrogen
are made
naturally by the
human body?

  • A 1
  • C 4
  • B 2
  • D More than 4

the quiz 3 of 6

How many types of estrogen are available in
almost all birth control pills?

  • A 1
  • C 4
  • B 2
  • D More than 4

the quiz 4 of 6

About how long has it been since there was a
new type of estrogen used in birth control pills?

  • A 5 years
  • C 60 years
  • B 40 years
  • D 100 years

the quiz 5 of 6

E4 (estetrol) works in the body
the same way as E2 (estradiol).

  • A True
  • B False

the quiz 6 of 6

The same E4 (estetrol) that is made by the
human body can be made from a plant source.

  • A True
  • B False

QUIZ RESULTS

You got 0 right.

Nice try!
Nothing wrong with being an estrogen novice. It’s
pretty much why we made this quiz and a website about
the birth control pill that contains E4 here .

The bottom line on E4 (estetrol)

Nextstellis is the first and only
FDA-approved
birth control pill with E4

E4 has selective actions in tissues, making it gentle on the breasts and liver while helping regulate your cycle. This naturally occurring human estrogen circulates between mother and baby during pregnancy. On top of that, E4 can be made from a plant source. Pretty neat, right?

And what’s even better is now you have a choice in the matter when it comes to the type of estrogen you want in your birth control pills.

Learn about the
only birth
control pill that contains E4

What is NEXTSTELLIS?

NEXTSTELLIS is a prescription combination oral birth control pill used for the prevention of pregnancy. NEXTSTELLIS does not protect against HIV infections (AIDS) and other sexually transmitted diseases. NEXTSTELLIS may be less effective if you have a body mass index (BMI) of 30 or higher. It is not known if NEXTSTELLIS is safe and effective in females with a body mass index (BMI) of 35 or higher. If you are moderately obese, discuss with your healthcare provider whether NEXTSTELLIS is appropriate for you.

WHAT IS THE MOST IMPORTANT INFORMATION I SHOULD KNOW ABOUT NEXTSTELLIS?

WARNING TO FEMALES WHO SMOKE
Do not use NEXTSTELLIS if you smoke cigarettes and are over 35 years old. Smoking increases your risk of serious cardiovascular side effects (heart and blood vessel problems) from birth control pills, including death from heart attack, blood clots, or stroke. This risk increases with age and the number of cigarettes you smoke.

Who should not take NEXTSTELLIS?

Do not use NEXTSTELLIS if you smoke and are 35 years of age or older. Do not use NEXTSTELLIS if you have or have had blood clots, history of heart attack, stroke or certain heart valve problems, high blood pressure that medicine cannot control, diabetes for more than 20 years, severe migraine headaches with aura, breast cancer or any cancer that is sensitive to female hormones, liver disease or liver tumors, unexplained bleeding from the vagina, have kidney disease or kidney failure, have reduced adrenal gland function, or if you take Hepatitis C drugs containing ombitasvir/paritaprevir/ritonavir, with or without dasabuvir, as this may increase levels of liver enzymes in the blood.

What else should I know about taking NEXTSTELLIS?

Before taking NEXTSTELLIS, tell your healthcare provider about all of your medical conditions, including if you:

  • are scheduled for surgery. NEXTSTELLIS may increase your risks of blood clots after surgery. Talk to your healthcare provider about taking NEXTSTELLIS before and after your surgery or if you are going to be unable to walk for an extended period of time.
  • are depressed now or have been depressed in the past.
  • had yellowing of your skin or eyes caused by pregnancy.
  • are pregnant or think you may be pregnant.
  • are breastfeeding or plan to breastfeed. NEXTSTELLIS may decrease the amount of breast milk you make. NEXTSTELLIS may pass into your breastmilk. Talk to your healthcare provider about the best birth control method for you while breastfeeding.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. NEXTSTELLIS may affect the way other medicines work, and other medicines may affect how well NEXTSTELLIS works.

What are the most serious risks of taking NEXTSTELLIS?

NEXTSTELLIS may cause serious side effects that may lead to death including blood clots in your lungs, heart attack, or a stroke. Some other examples of serious blood clots include blood clots in the legs or eyes. Other serious risks include high potassium levels in your blood, high blood pressure, new or worsening headaches including migraine headaches, possible cancer that is sensitive to female hormones, liver problems, changes in the sugar and fat blood levels, gallbladder problems, irregular or unusual vaginal bleeding, spotting, or absence of menstrual periods, depression, possible cancer of the cervix, swelling of the skin especially around the mouth, eyes, and in the throat, and dark patches of skin around your forehead, nose, cheeks, and around your mouth, especially during pregnancy.

What are the possible side effects of NEXTSTELLIS?

The most common side effects reported by females taking NEXTSTELLIS in a study were spotting or bleeding between menstrual periods, mood changes, headache, breast tenderness, pain and discomfort, painful periods, acne, weight gain, and decreased sex drive.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call
1-800-FDA-1088.

Please see the full Prescribing Information, including Boxed Warning, and Patient Information.

Top

indication

NEXTSTELLIS is a prescription combination oral birth
control pill used for the prevention of pregnancy.
NEXTSTELLIS does not protect against HIV infections (AIDS) and other sexually transmitted diseases. NEXTSTELLIS may be less effective if you have a body mass index (BMI) of 30 or higher. It is not known if NEXTSTELLIS is safe and effective in females with a body mass index (BMI) of 35 or higher. If you are moderately obese, discuss with your healthcare provider whether NEXTSTELLIS is appropriate for you.

Important Safety Information

WARNING TO FEMALES WHO SMOKE

Do not use NEXTSTELLIS if you smoke cigarettes and are over 35 years old. Smoking increases your risk of serious cardiovascular side effects (heart and blood vessel problems) from birth control pills, including death from heart attack, blood clots, or stroke. This risk increases with age and the number of cigarettes you smoke.